Th e article presents the basic elements of entrepreneurial activities considered from the point of view of praxeology and ethics, in reference to previous foreign and domestic publications. Th e praxiological approach to entrepreneurship was outlined both according to the praxiology derived from Kotarbiński’s school and Misesian praxeology. The characteristics of entrepreneurship related to monotheistic religions were presented, while the fragments of the papal encyclicals in which they refer directly to entrepreneurship activities are quoted. Issues related to the ethical dimension of entrepreneurship were noted, with particular emphasis on the manipulations and frauds of the contemporary business and economy criticized in the literature. Responsible entrepreneurship should observe the technological imperative.