In the past years we observed changes in the structures of knowledge production. The new mode of research expects intensive collaboration among multiple stakeholders in order to ensure the social relevance of knowledge. Such a development has led many theorists to question the epistemological status of findings, and the relevance of such studies, since this mode of research might transpire rather alarmingly to serve the interests of a small influential group. By discussing the two views, the paper sides with the argument that science has evolved into a closed, self-governed system; thus, any change in the governance of knowledge production puts at stake its status and role in society –which is to serve the ‘public good’. In the same line of argument, it seconds that the ethical construction of knowledge has to become the scientists’ main concern, who need to be conscious not only of positive, but also of negative implications of their findings. Finally, the paper concludes with a number of suggestions, which may contribute to the ethical construction of knowledge.